In November 2021, the Federal Reserve Bank of New York, the European Commission, and CEPR brought together US- and European-based policymakers and economists from academia, think tanks, and international financial institutions to discuss issues that transatlantic policymakers are facing. This column summarises the principal themes and findings of the conference discussion on questions such as how to support growth while addressing inflationary pressures, facilitating the climate transition, and reducing economic inequalities; what the key changes are in the Federal Reserve’s and ECB’s new monetary policy frameworks; and how best to consolidate public finances.